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Cancer genetic testing

Germline/Hereditary cancer genetic testing / Personalized medicine / Genome medicine / Precision medicine / Preventative medicine

CEN4GEN offers a large assortment of testing options for hereditary cancer, involving many organ systems, for those individuals who have a family history of cancer and are concerned about their risk of developing some form of cancer.

We offer:

  • single full gene sequencing
  • single gene deletion/duplication analysis
  • single gene full gene sequencing and gene deletion/duplication analysis
  • gene panel full gene sequencing
  • gene panel deletion/duplication analysis
  • gene panel full gene sequencing and gene deletion/duplication analysis
  • customized testing
  • known mutation analysis

Methods

We use a variety of methods, including:

  • Next generation sequencing
  • Array CGH
  • Array SNP
  • Computational analysis of next generation sequencing data to ascertain regions of deletion/duplication
  • MLPA
  • Sanger sequencing
  • Pyrosequencing
  • FISH

Specimen requirements:

Germline conditions:

2 vials of whole blood in EDTA, or saliva collected in a collection tube approved by CEN4GEN or 3 to 5 ug of DNA in TE buffer.

For FISH analysis, 2 vials of whole blood in Heparin is required.

Requesting a test:

To learn more, you must contact CEN4GEN for more information, and we will evaluate your testing needs on a case by case basis. You will need to send us the following information regarding your testing request:

a) name of condition (if known)
b) name of gene(s) (if known)
c) type of testing request: sequencing, deletion/duplication, known mutation analysis
 

Somatic genetic testing

CEN4GEN offers a wide spectrum of testing options for those patients who already have some form of cancer.  CEN4GEN undertakes direct testing on the cancer/tumor specimen, in a procedure known as somatic genetic testing.  This method is used to identify specific molecular mutations in the tumor/cancer which could assist in establishing a more precise diagnosis, understanding the tumor/cancer properties, patient prognosis, as well as tumor/cancer behavior.

We offer:

  • single full gene sequencing
  • single gene deletion/duplication analysis
  • single gene full gene sequencing and gene deletion/duplication analysis
  • gene panel full gene sequencing
  • gene panel deletion/duplication analysis
  • gene panel full gene sequencing and gene deletion/duplication analysis
  • customized testing
  • known mutation analysis

Methods

We use a variety of methods, including:

  • Next generation sequencing
  • Array CGH
  • Array SNP
  • Computational analysis of next generation sequencing data to ascertain regions of deletion/duplication
  • Sanger sequencing
  • Pyrosequencing
  • FISH

Specimen requirements:

2 vials of whole blood in EDTA, or saliva collected in a collection tube approved by CEN4GEN or 3 to 5 ug of DNA in TE buffer.

AND

1 FFPE block or 15 to 20 FFPE slides or frozen tumor tissue/cell pellet. We also accept 2 tubes of whole blood in a CTC (circulating tumor cell) blood collection tube approved by CEN4GEN.  Contact CEN4GEN for more information.

Requesting a test:

To learn more, you must contact CEN4GEN for more information, and we will evaluate your testing needs on a case by case basis. You will need to send us the following information regarding your testing request:

a) name of condition (if known)
b) name of gene(s) (if known)
c) type of testing request: sequencing, deletion/duplication, known mutation analysis
 

CEN4GEN cancer precision diagnostic testing / genome medicine / personalized medicine / preventative medicine services

CEN4GEN offers state-of-the art cancer precision diagnostic medicine services.  We help cancer patients by undertaking extensive genomics analysis of a wide spectrum of cancers/tumors. We provide an in depth report of medically actionable findings that have relevance to current approved therapies, off label therapies/investigational therapies, therapies with negative effects (contraindicated therapies), tumor biomarkers (which help predict factors such as patient survival and cancer aggressiveness), compatibility to immunotherapy and experimental clinical trials that patients can potentially enroll in. This CEN4GEN Cancer precision medicine test is suitable for cancer patients a) who have any forms of cancer, b) require a thorough cancer biomarker profiling to assist in diagnosis, treatment and survival prediction, c) have cancers of either known or unknown primary origin. Our in depth service is tailored to help doctors and their patients determine the most effective patient care and treatment. CEN4GEN cancer precision diagnostic testing service overall helps in more efficient, improved accuracy and cost effective patient care, and could lead to better quality of life and more successful treatments for cancer patients.  Please contact CEN4GEN at [email protected] to learn more about our cancer precision diagnostic testing services, and the different types of testing options available.

Specimen requirements:

2 vials of whole blood in EDTA, or saliva collected in a collection tube approved by CEN4GEN or 3 to 5 ug of DNA in TE buffer.

AND

1 FFPE block or 15 to 20 FFPE slides or frozen tumor tissue/cell pellet. We also accept 2 tubes of whole blood in a CTC (circulating tumor cell) blood collection tube approved by CEN4GEN. Contact CEN4GEN for more information.

Requesting a test:

To learn more, you must contact CEN4GEN for more information, and we will evaluate your testing needs on a case by case basis. You will need to send us the following information regarding your testing request:

a) name of cancer condition (if known)

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NOTABLE ACCOMPLISHMENTS

CEN4GEN: Genetic Testing | Genome Medicine | Personalized Medicine

Genome medicine services:

Founded in 2014, CEN4GEN® is the first private commercial provider in Canada to develop and launch several proprietary and certain unique testing options, which have relevance to DNA testing / Genetic testing / Genome Medicine / Precision Medicine / Personalized Medicine / Preventive Medicine for:

  • Clinical Whole genome / Personal Whole Genome (genomics based)
  • Newborn screen (genomics based)
  • Cancer precision medicine (genomics based)
  • Most comprehensive list of medications in pharmacogenomic/pharmacogenetics screen (genomics based)
  • Clinical metagenomics (genomics based)
  • Preimplantation testing with full gene panel / exome / whole genome screening (genomics based)
  • Liquid biopsy for certain diagnostic applications (genomics based)
  • Genomics based combined molecular diagnostic testing and customized companion diagnostics including for cardiovascular, cancer, neurodegenerative, and neurological disorders
CEN4GEN: Genetic Testing | Genome Medicine | Personalized Medicine CEN4GEN: Genetic Testing | Genome Medicine | Personalized Medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine

CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic testing | Genome Medicine | Personalized medicine | DNA testing | Precision medicine
CEN4GEN: Genetic Testing | Genome Medicine | Personalized Medicine
CEN4GEN: Genetic Testing | Genome Medicine | Personalized Medicine
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